Quality Immune Cells
For Your Research

Antigen-specific T cells (ASpecT) are an important tool in T cell biology research and potency assays. Investigators can isolate them directly from the disease site (e.g., tumor-infiltrating lymphocytes (TIL) or inflammatory lesion infiltrate populations), but these procedures often yield a limited number of cells due to low cell frequency and lack of robust isolation methods. Alternatively, antigen-specific T cells can be generated in vitro using antigen-presenting cells pulsed with whole antigens or peptides. However, this process is often time-consuming with a low success rate.

Ignyte Bio offers antigen-specific T cells (ASpecT) for research use you can rely on.

• Typically generated using multiple in vitro stimulations with peptide antigens
• Not immortalized or genetically modified, so they more closely mimic physiological T cells
• Specificity analyzed using the cognate peptide/MHC tetramer binding as well as interferon-gamma (IFN-γ) secretion and cytotoxicity assays.

Here is a growing list of Ignyte Bio Antigen-Specific T Cells (ASpecT) products.

Cat. No.	Antigen Type	Antigen
TC-05	tumor	gp-100
TC-06	tumor	Tyrosinase
TC-07	tumor	MART-1
TC-08	tumor	NY-ESO-1
TC-11	tumor	MUC1
CST-01	virus	HPV E711-20
TC-10	virus	CMV
TC-12	virus	EBV