Anti-HPV E7(11-20) CD8+ T Cells

$700.00

  • Product Size: ≥ 1M  
  • Catalog Number: CST-01   
  • Donor Number: 115   
  • Stock Left: 99
  • Lot Number: 00860922
  • C.of.A: link

99 in stock

Description

Human papillomavirus (HPV) infection, particularly type 16, is associated with the development of cervical cancer. The constitutively expressed HPV principal transforming protein E7 makes an attractive target for T cell based immunotherapy. One of the E7 peptides, HPV E711-20 (YMLDLQPETT), has been identified as one of the epitopes for CD8+ T cells detected in individuals with cervical cancer. IGNYTE BIO offers CD8+ T cells specific for HPV E711-20 (YMLDLQPETT) in association with HLA-A*0201. Antigen-specificity is demonstrated by tetramer binding as well as functional studies (specific IFN-gamma release and cytotoxicity)

Additional information

Donor #

115

Donor Age

58

Gender

F

Ethnicity

Caucasian

Donor Health

Normal

Smoker Status

N

Blood Type

B-

CMV Status

Pos

Fcgr3a-158 genotype

F/F

HLA-A

02:01, 02:01

HLA-B

07:02, 15:01

HLA-C

03:03, 07:02

HLA-DRB1

13:01, 15:01

HLA-DPA1

01:03, 01:03

HLA-DPB1

02:01, 04:01

HLA-DQA1

01:02, 01:03

HLA-DQB1

06:02, 06:03

BMI

39